Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

ABSTRACT Neuropathic pain (NPP) is a critical clinical challenge with limited therapeutic options. While neuronal mechanisms have been extensively studied, the contribution of oligodendrocyte (OL) homeostasis to NPP pathogenesis is poorly understood. Here, we show that chronic constriction injury (C...

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Autores principales:	Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2026-07-01
Colección:	Advanced Science
Materias:	c‐Myc myelin neuropathic pain oligodendrocyte PDK1 SOX10
Acceso en línea:	https://doi.org/10.1002/advs.202516426
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