Synthesis, Structure–Activity Relationships and In Vitro Toxicity Profile of Lactose-Based Fatty Acid Monoesters as Possible Drug Permeability Enhancers

Permeability enhancers are receiving increased attention arising from their ability to increase transepithelial permeability and thus, bioavailability of orally or pulmonary administered biopharmaceutics. Here we present the synthesis and the in vitro assaying of a series of lactose-based non-ionic...

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Detalhes bibliográficos

Principais autores:	Simone Lucarini, Laura Fagioli, Robert Cavanagh, Wanling Liang, Diego Romano Perinelli, Mario Campana, Snjezana Stolnik, Jenny K. W. Lam, Luca Casettari, Andrea Duranti
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2018-07-01
coleção:	Pharmaceutics
Assuntos:	absorption enhancers sugar-based surfactants biocompatibility studies transmucosal drug delivery
Acesso em linha:	http://www.mdpi.com/1999-4923/10/3/81
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