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B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells

Aim: T-helper cells could play an important role in the pathogenesis of chronic lymphocytic leukemia (CLL), a common B-cell neoplasm. Although CLL cells can present soluble antigens targeted from the B-cell receptor to T-helper cells via major histocompatibility complex (MHC) class II, antigens rec...

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Hoofdauteurs: Annabel R. Minton, Lindsay D. Smith, Dean J. Bryant, Jonathan C. Strefford, Francesco Forconi, Freda K. Stevenson, Edd James, Geir Åge Løset, Ludvig A. Munthe, Andrew J. Steele, Graham Packham
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Open Exploration Publishing Inc. 2022-02-01
Reeks:Exploration of Targeted Anti-tumor Therapy
Onderwerpen:
chronic lymphocytic leukemia
antigen presentation
t helper cell
b-cell receptor
phagocytosis
major histocompatibility complex class ii
human leukocyte antigen class ii
Online toegang:https://www.explorationpub.com/Journals/etat/Article/100270
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