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Human B-1 cells are important contributors to the naturally-occurring IgM pool against the tumor-associated ganglioside Neu5GcGM3

Only few studies have described the anti-tumor properties of natural antibodies (NAbs). In particular, natural IgM have been linked to cancer immunosurveillance due to its preferential binding to tumor-specific glycolipids and carbohydrate structures. Neu5GcGM3 ganglioside is a sialic acid–containin...

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Hlavní autoři: Nely Rodriguez-Zhurbenko, Tam D. Quach, Thomas L. Rothstein, Ana M. Hernandez
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-11-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1061651/full
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