Elucidation of the Conformational Transition of Oligopeptidase B by an Integrative Approach Based on the Combination of X-ray, SAXS, and Essential Dynamics Sampling Simulation

Oligopeptidase B (OPB) is the least studied group from the prolyl oligopeptidase family. OPBs are found in bacteria and parasitic protozoa and represent pathogenesis factors of the corresponding infections. OPBs consist of two domains connected by a hinge region and have the characteristics of confo...

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Hlavní autoři:	Vladimir V. Britikov, Vladimir I. Timofeev, Dmitry E. Petrenko, Elena V. Britikova, Alena Y. Nikolaeva, Anna V. Vlaskina, Konstantin M. Boyko, Anna G. Mikhailova, Tatiana V. Rakitina
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-05-01
Edice:	Crystals
Témata:	crystal structure prolyl oligopeptidase oligopeptidase B intermediate state hinge region X-ray diffraction analysis
On-line přístup:	https://www.mdpi.com/2073-4352/12/5/712
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