Elucidation of the Conformational Transition of Oligopeptidase B by an Integrative Approach Based on the Combination of X-ray, SAXS, and Essential Dynamics Sampling Simulation

Oligopeptidase B (OPB) is the least studied group from the prolyl oligopeptidase family. OPBs are found in bacteria and parasitic protozoa and represent pathogenesis factors of the corresponding infections. OPBs consist of two domains connected by a hinge region and have the characteristics of confo...

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Библиографические подробности

Главные авторы:	Vladimir V. Britikov, Vladimir I. Timofeev, Dmitry E. Petrenko, Elena V. Britikova, Alena Y. Nikolaeva, Anna V. Vlaskina, Konstantin M. Boyko, Anna G. Mikhailova, Tatiana V. Rakitina
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2022-05-01
Серии:	Crystals
Предметы:	crystal structure prolyl oligopeptidase oligopeptidase B intermediate state hinge region X-ray diffraction analysis
Online-ссылка:	https://www.mdpi.com/2073-4352/12/5/712
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