Ischemic Preconditioning Confers Epigenetic Repression of Mtor and Induction of Autophagy Through G9a‐Dependent H3K9 Dimethylation

Background Ischemic preconditioning (IPC) protects the heart from prolonged ischemic insult and reperfusion injury through a poorly understood mechanism. Post‐translational modifications of histone residues can confer rapid and drastic switches in gene expression in response to various stimuli, incl...

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Autores principales:	Olof Gidlöf, Andrea L. Johnstone, Kerstin Bader, Bohdan B. Khomtchouk, Jiaqi J. O'Reilly, Selvi Celik, Derek J. Van Booven, Claes Wahlestedt, Bernhard Metzler, David Erlinge
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2016-12-01
Colección:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Materias:	autophagy epigenetics ischemia
Acceso en línea:	https://www.ahajournals.org/doi/10.1161/JAHA.116.004076
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