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Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development

The HIV-1 genome is malleable and a difficult target tot vaccinate against. It has long been recognised that cytotoxic T lymphocytes and neutralising antibodies readily select for immune escape HIV variants. It is now also clear that NK cells can also select for immune escape. NK cells force immune...

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Bibliografiske detaljer
Principais autores: Gamze Isitman, Ivan Stratov, Stephen J. Kent
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2012-01-01
Serier:Advances in Virology
Online adgang:http://dx.doi.org/10.1155/2012/637208
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