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Antibody-Dependent Cellular Cytotoxicity and NK Cell-Driven Immune Escape in HIV Infection: Implications for HIV Vaccine Development

The HIV-1 genome is malleable and a difficult target tot vaccinate against. It has long been recognised that cytotoxic T lymphocytes and neutralising antibodies readily select for immune escape HIV variants. It is now also clear that NK cells can also select for immune escape. NK cells force immune...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Gamze Isitman, Ivan Stratov, Stephen J. Kent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2012-01-01
Schriftenreihe:Advances in Virology
Online-Zugang:http://dx.doi.org/10.1155/2012/637208
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