Repair or Degrade: the Thermodynamic Dilemma of Cellular Protein Quality-Control

Life is a non-equilibrium phenomenon. Owing to their high free energy content, the macromolecules of life tend to spontaneously react with ambient oxygen and water and turn into more stable inorganic molecules. A similar thermodynamic picture applies to the complex shapes of proteins: While a polype...

詳細記述

書誌詳細

主要な著者:	Bruno Fauvet, Mathieu E. Rebeaud, Satyam Tiwari, Paolo De Los Rios, Pierre Goloubinoff
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2021-10-01
シリーズ:	Frontiers in Molecular Biosciences
主題:	proteostasis thermodynamics protein repair chaperones protein degradation
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fmolb.2021.768888/full
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