Metformin attenuates cuprizone-induced mitochondrial dysfunction and senescence-associated changes in primary neuronal cells
Mitochondrial dysfunction and cellular senescence are key features of brain aging and neurodegenerative diseases. Cuprizone (CPZ), a mitochondrial toxin, induces oxidative stress, abnormal lipid metabolism, and iron accumulation in neurons and oligodendrocytes. Here, we investigated whether metformi...
Zapisane w:
| Główni autorzy: | , , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Japan Society for Cell Biology
2026-05-01
|
| Seria: | Cell Structure and Function |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.jstage.jst.go.jp/article/csf/51/1/51_26019/_html/-char/en |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|