Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction

Background Inflammation and metabolic disorders are important factors in the occurrence and development of obesity complications. In this study, we investigated the protective effect and underlying mechanism of a novel pyrimidine-2,4-diamine derivative, Cyy-287, on mice fed a high-fat diet (HFD). Me...

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Xehetasun bibliografikoak
Egile Nagusiak:	Jinhuan Ni, Xiaodan Zhang, Huijing Huang, Zefeng Ni, Jianchao Luo, Yunshan Zhong, Min Hui, Zhiguo Liu, Jianchang Qian, Qianwen Zhang
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	PeerJ Inc. 2024-02-01
Saila:	PeerJ
Gaiak:	Cyy-287 Inflammation Obesity complications Ventricular remodeling Hepatic steatosis NF-kB
Sarrera elektronikoa:	https://peerj.com/articles/17009.pdf
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Cyy-287, a novel pyrimidine-2,4-diamine derivative, efficiently mitigates inflammatory responses, fibrosis, and lipid synthesis in obesity-induced cardiac and hepatic dysfunction

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