Metformin activated AMPK signaling contributes to the alleviation of LPS-induced inflammatory responses in bovine mammary epithelial cells

Abstract Background Lipopolysaccharides (LPS) derived from gram-negative bacterial are often regarded as primary inducer of bovine mammary inflammation. This study evaluated the biological response of metformin activated AMPK signaling on LPS-induced inflammatory responses and metabolic changes in p...

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Autores principales:	Tianle Xu, Xinyue Wu, Xubin Lu, Yusheng Liang, Yongjiang Mao, Juan J. Loor, Zhangping Yang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2021-03-01
Colección:	BMC Veterinary Research
Materias:	pbMEC Inflammation Metformin AMPK signaling Metabolic changes
Acceso en línea:	https://doi.org/10.1186/s12917-021-02797-x
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