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Metformin activated AMPK signaling contributes to the alleviation of LPS-induced inflammatory responses in bovine mammary epithelial cells

Abstract Background Lipopolysaccharides (LPS) derived from gram-negative bacterial are often regarded as primary inducer of bovine mammary inflammation. This study evaluated the biological response of metformin activated AMPK signaling on LPS-induced inflammatory responses and metabolic changes in p...

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Principais autores: Tianle Xu, Xinyue Wu, Xubin Lu, Yusheng Liang, Yongjiang Mao, Juan J. Loor, Zhangping Yang
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2021-03-01
סדרה:BMC Veterinary Research
נושאים:
pbMEC
Inflammation
Metformin
AMPK signaling
Metabolic changes
גישה מקוונת:https://doi.org/10.1186/s12917-021-02797-x
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