A conserved ER protein prevents lipotoxicity by stimulating the key enzyme in glycerolipid synthesis
Abstract The synthesis of glycerolipid is essential to prevent the toxic effects of excess fatty acids. Glycerolipids are generated by the sequential attachment of acyl-CoA to glycerol by endoplasmic reticulum (ER)-localized acyltransferases, ultimately yielding non-toxic triacylglycerol that can be...
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| Hoofdauteurs: | , , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
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Nature Portfolio
2026-05-01
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| Reeks: | Nature Communications |
| Online toegang: | https://doi.org/10.1038/s41467-026-72786-x |
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