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A comprehensive computational study to explore promising natural bioactive compounds targeting glycosyltransferase MurG in Escherichia coli for potential drug development

Abstract Peptidoglycan is a carbohydrate with a cross-linked structure that protects the cytoplasmic membrane of bacterial cells from damage. The mechanism of peptidoglycan biosynthesis involves the main synthesizing enzyme glycosyltransferase MurG, which is known as a potential target for antibioti...

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Autors principals: Amneh Shtaiwi, Shafi Ullah Khan, Meriem Khedraoui, Mohd Alaraj, Abdelouahid Samadi, Samir Chtita
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2024-03-01
Col·lecció:Scientific Reports
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Accés en línia:https://doi.org/10.1038/s41598-024-57702-x
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