Anti-inflammatory effect of fluvastatin on polarized macrophages and its dependence on the mevalonate pathway

Abstract The study focuses on the effects of fluvastatin on immunomarkers of the M1 and M2 macrophages and its direct role in macrophage (M0) polarization. Moreover, it investigates the dependency of immunomodulatory properties of fluvastatin on the mevalonate pathway. Macrophages (M0, M1, M2), diff...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Barbora Muffova, Sona Kauerova, Karel Paukner, Hana Bartuskova, Rudolf Poledne, Ivana Kralova Lesna
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2025-06-01
Serija:Scientific Reports
Teme:
Fluvastatin
Macrophages
Polarization
Inflammation
Mevalonate pathway
Online dostop:https://doi.org/10.1038/s41598-025-02418-9
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki