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Recent advances in natural products targeting α-synuclein aggregation or clearance in Parkinson's disease

Parkinson's disease is a neurodegenerative disorder characterized by the accumulation of misfolded α-synuclein fibrils, leading to the formation of Lewy bodies. Currently, no effective treatment exists to halt the progression of the disease. Only symptomatic relief and dopamine replacement therapy a...

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Autori principali: Jay Gupta, Koneni V. Sashidhara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2023-12-01
Serie:European Journal of Medicinal Chemistry Reports
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2772417423000146
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