Recent advances in natural products targeting α-synuclein aggregation or clearance in Parkinson's disease

Parkinson's disease is a neurodegenerative disorder characterized by the accumulation of misfolded α-synuclein fibrils, leading to the formation of Lewy bodies. Currently, no effective treatment exists to halt the progression of the disease. Only symptomatic relief and dopamine replacement therapy a...

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Detalhes bibliográficos

Principais autores:	Jay Gupta, Koneni V. Sashidhara
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-12-01
coleção:	European Journal of Medicinal Chemistry Reports
Assuntos:	Parkinson's disease Neurodegenerative disorder α-Synuclein Amyloid fibrils Inhibitors Natural products
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2772417423000146
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