Generation and characterization of two acid-resistant macrocin O-methyltransferase variants with a higher enzyme activity at 30 °C from Streptomyces fradiae
Tylosin is an important macrolide antibiotic produced by Streptomyces fradiae. In the biosynthesis of tylosin, macrocin O-methyltransferase TylF catalyzes the conversion of the side-product tylosin C (macrocin) to the primary component tylosin A (C/A conversion). This conversion is the rate-limiting...
Na minha lista:
| Principais autores: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science (AAAS)
2024-12-01
|
| Colecção: | Computational and Structural Biotechnology Journal |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2001037024002794 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|