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Binding Orientations and Lipid Interactions of Human Amylin at Zwitterionic and Anionic Lipid Bilayers

Increasing evidence suggests that the interaction of human islet amyloid polypeptide (hIAPP) with lipids may facilitate hIAPP aggregation and cause the death of pancreatic islet β-cells. However, the detailed hIAPP-membrane interactions and the influences of lipid compositions are unclear. In this s...

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Detalles Bibliográficos
Autores principales: Zhenyu Qian, Yan Jia, Guanghong Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley 2016-01-01
Colección:Journal of Diabetes Research
Acceso en línea:http://dx.doi.org/10.1155/2016/1749196
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