Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-<i>b</i>]indole Derivative, Discovered as CK2 Inhibitor

Protein kinase CK2 is involved in regulating cellular processes, such as cell cycle, proliferation, migration, and apoptosis, making it an attractive anticancer target. We previously described a prenyloxy-substituted indeno[1,2-<i>b</i>]indole (5-isopropyl-4-(3-methylbut-2-enyloxy)-5,6,7,8-tetrahydr...

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Detalhes bibliográficos

Principais autores:	Ehab El-Awaad, Robin Birus, Christelle Marminon, Zouhair Bouaziz, Laurens Ballentin, Dagmar Aichele, Marc Le Borgne, Joachim Jose
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-06-01
coleção:	Pharmaceuticals
Assuntos:	CK2 inhibitor indeno[1,2-<i>b</i>]indole anticancer pharmacokinetics LC-MS
Acesso em linha:	https://www.mdpi.com/1424-8247/14/6/542
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