The protective effects of rapamycin on cell autophagy in the renal tissues of rats with diabetic nephropathy via mTOR-S6K1-LC3II signaling pathway

Background: Previous studies have shown that podocyte autophagy is an important trigger for proteinuria and glomerulosclerosis. The mammalian rapamycin target protein (mTOR) occupies a pivotal position in the autophagy pathway. In this study, we planned to clarify the mechanism of mTOR regulation of...

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Hlavní autoři:	Lei Liu, Lijuan Yang, Baochao Chang, Jiqiang Zhang, Yaling Guo, Xiangdong Yang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2018-10-01
Edice:	Renal Failure
Témata:	Diabetic nephropathy podocyte autophagy mTOR rapamycin
On-line přístup:	http://dx.doi.org/10.1080/0886022X.2018.1489287
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