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Higher levels of GluN1 splice cassettes, C2 and C2’, in hippocampus of aged mice were associated with poor spatial reference memory

Cognitive decline during aging has been linked to changes in the N-methyl-D-aspartate receptor (NMDAR). Age-related changes in the GluN1 splice cassette proteins have been described in crude synaptosomes, but synaptic and extrasynaptic NMDARs have different impacts on synaptic plasticity. The presen...

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Autores principales: Kathy R. Magnusson, Daniel R. Zamzow
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2025-10-01
Colección:Brain Research Bulletin
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S0361923025003144
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