Matching for HLA-DR excluding diabetogenic HLA-DR3 and HLA-DR4 predicts insulin independence after pancreatic islet transplantation

IntroductionIn pancreatic islet transplantation, the exact contribution of human leukocyte antigen (HLA) matching to graft survival remains unclear. Islets may be exposed to allogenic rejection but also the recurrence of type 1 diabetes (T1D). We evaluated the HLA-DR matching, including the impact o...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Cassandra Ballou, Franca Barton, Elizabeth H. Payne, Thierry Berney, Jean Villard, Raphael P. H. Meier, David Baidal, Rodolfo Alejandro, Mark Robien, Thomas L. Eggerman, Malek Kamoun, Yannick D. Muller
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2023-03-01
Sarja:	Frontiers in Immunology
Aiheet:	islet transplantation HLA-DR4 HLA-DR3 insulin independence type 1 diabetes insulin
Linkit:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1110544/full
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