SLC38A9 is directly involved in Tat-induced endolysosome dysfunction and senescence in astrocytes
Internalized HIV Tat interacts with endolysosome-resident SLC38A9 via the arginine-rich domain, and such an interaction leads to endolysosome dysfunction and cellular senescence in human astrocytes. Cellular senescence contributes to accelerated aging and the development of various neurodegeneration...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Life Science Alliance LLC
2025-07-01
|
| Schriftenreihe: | Life Science Alliance |
| Online-Zugang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503231 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|