Path‐seq identifies an essential mycolate remodeling program for mycobacterial host adaptation

Abstract The success of Mycobacterium tuberculosis (MTB) stems from its ability to remain hidden from the immune system within macrophages. Here, we report a new technology (Path‐seq) to sequence miniscule amounts of MTB transcripts within up to million‐fold excess host RNA. Using Path‐seq and regul...

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Principais autores:	Eliza JR Peterson, Rebeca Bailo, Alissa C Rothchild, Mario L Arrieta‐Ortiz, Amardeep Kaur, Min Pan, Dat Mai, Abrar A Abidi, Charlotte Cooper, Alan Aderem, Apoorva Bhatt, Nitin S Baliga
格式:	Artigo
語言:	Inglês
出版:	Springer Nature 2019-03-01
叢編:	Molecular Systems Biology
主題:	gene regulatory networks host–pathogen interactions Mycobacterium tuberculosis Path‐seq systems biology
在線閱讀:	https://doi.org/10.15252/msb.20188584
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