Administering Bifidobacterium pseudolongum With Arsenic Trioxide Attenuates Acute Promyelocytic Leukemia in Mice by Restoring Immune Microenvironment and Intestinal Homeostasis

Objective: Arsenic trioxide (ATO) is a cornerstone of acute promyelocytic leukemia (APL) therapy but induces severe gut microbiota dysbiosis, limiting its efficacy and safety. This study investigated whether adjunctive Bifidobacterium pseudolongum (BP) could mitigate these adverse...

Disgrifiad llawn

Manylion Llyfryddiaeth

Prif Awduron:	Zhibo Guo, Zengliang Gao, Yanqiu Zhao, Xiaoting Ni, Wenlei Zhang, Longyu Li, Shiao Ren, Qi Li, Dan Guo, Lijuan Yue, Yutong Liu, Liwang Lin, Shengjin Fan, Xin Hai
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	IMR Press 2026-02-01
Cyfres:	Frontiers in Bioscience-Landmark
Pynciau:	arsenic trioxide acute promyelocytic leukemia intestinal homeostasis bone marrow microenvironment bifidobacterium pseudolongum
Mynediad Ar-lein:	https://www.imrpress.com/journal/FBL/31/2/10.31083/FBL48584
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!