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Revealing the immune cell subtype reconstitution profile in patients from the CLARITY study using deconvolution algorithms after cladribine tablets treatment

Abstract Immune Cell Deconvolution methods utilizing gene expression profiling to quantify immune cells in tissues and blood are an appealing alternative to flow cytometry. Our objective was to investigate the applicability of deconvolution approaches in clinical trial settings to better investigate...

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Principais autores: Irina Kalatskaya, Gavin Giovannoni, Thomas Leist, Joseph Cerra, Ursula Boschert, P. Alexander Rolfe
格式: Artigo
語言:Inglês
出版: Nature Portfolio 2023-05-01
叢編:Scientific Reports
在線閱讀:https://doi.org/10.1038/s41598-023-34384-5
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