DNA methylation signatures of bilateral hippocampal volume, asymmetry and atrophy: a cross-omics analysis in the general populationResearch in context

Summary: Background: Left-right hippocampal volumetric asymmetry and atrophy are implicated in neurodegenerative and neuropsychiatric disorders, yet their molecular basis in healthy adults remains poorly understood. Methods: We conducted a meta-analysis of epigenome-wide association studies across...

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Hlavní autoři:	Dan Liu, Valentina Talevi, Juliana F. Tavares, Ruiqi Wang, Mohammed A. Imtiaz, Konstantinos Melas, Alexander Teumer, Katharina Wittfeld, Robert F. Hillary, Dina Vojinovic, Marian Beekman, Nicola J. Armstrong, Santiago Estrada, Henry Völzke, Robin Bülow, Natalie A. Royle, Joanna M. Wardlaw, Wei Wen, Perminder S. Sachdev, Karen A. Mather, P. Eline Slagboom, Simon R. Cox, Hans Jörgen Grabe, Qiong Yang, N. Ahmad Aziz, Monique M.B. Breteler
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-06-01
Edice:	EBioMedicine
Témata:	Biomarker DNA methylation Hippocampal volume Hippocampal asymmetry Diet Population-based
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2352396426001714
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