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DNA methylation signatures of bilateral hippocampal volume, asymmetry and atrophy: a cross-omics analysis in the general populationResearch in context

Summary: Background: Left-right hippocampal volumetric asymmetry and atrophy are implicated in neurodegenerative and neuropsychiatric disorders, yet their molecular basis in healthy adults remains poorly understood. Methods: We conducted a meta-analysis of epigenome-wide association studies across...

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Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Dan Liu, Valentina Talevi, Juliana F. Tavares, Ruiqi Wang, Mohammed A. Imtiaz, Konstantinos Melas, Alexander Teumer, Katharina Wittfeld, Robert F. Hillary, Dina Vojinovic, Marian Beekman, Nicola J. Armstrong, Santiago Estrada, Henry Völzke, Robin Bülow, Natalie A. Royle, Joanna M. Wardlaw, Wei Wen, Perminder S. Sachdev, Karen A. Mather, P. Eline Slagboom, Simon R. Cox, Hans Jörgen Grabe, Qiong Yang, N. Ahmad Aziz, Monique M.B. Breteler
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2026-06-01
Rangatū:EBioMedicine
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Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2352396426001714
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