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Deciphering tumor-intrinsic and immune characteristics in resectable non-small cell lung cancer treated with neoadjuvant pembrolizumab and chemotherapy

Abstract Background Neoadjuvant chemo-immunotherapy (NCIT) aims to improve surgical and survival outcomes of non-small cell lung cancer (NSCLC) patients. However, the clinical application of NCIT still necessitates coordinated immune and molecular biomarker testing. Methods We conducted whole transc...

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Bibliografiske detaljer
Principais autores: Yulong Chen, Yanjun Su, Ran Zhang, Song Wang, Jiangyan Zhang, Xiaoxuan Sun, Gang Zhao, Qiuxiang Ou, Hua Bao, Jian You
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-10-01
Serier:Journal of Translational Medicine
Fag:
Online adgang:https://doi.org/10.1186/s12967-025-06965-7
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