PGC-1α overexpression promotes mitochondrial biogenesis to protect auditory cells against cisplatin-induced cytotoxicity
Abstract. Cisplatin (CDDP)-induced ototoxicity is one of the common adverse effects of cisplatin chemotherapy. Thus far, effective approaches for attenuating hearing loss are unavailable in clinical practice. Mitochondrial biogenesis acts as a master element of mitochondrial health and is necessary...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Association for the Advancement of Science (AAAS)
2019-06-01
|
| Schriftenreihe: | Journal of Bio-X Research |
| Online-Zugang: | http://journals.lww.com/10.1097/JBR.0000000000000038 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|