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Role of HNF4alpha-cMyc interaction in liver regeneration after partial hepatectomy

BackgroundHepatocyte nuclear factor 4 alpha (HNF4α) is the master regulator of hepatic differentiation. Recent studies have also revealed the role of HNF4α in hepatocyte proliferation via negatively regulating the expression of proto-mitogenic genes, including cMyc. Here, we aimed to study the inter...

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Bibliografiske detaljer
Principais autores: Manasi Kotulkar, Diego Paine-Cabrera, Kaitlyn Venneman, Udayan Apte
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-07-01
Serier:Frontiers in Endocrinology
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Online adgang:https://www.frontiersin.org/articles/10.3389/fendo.2024.1404318/full
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