An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape

BackgroundAlthough immunoglobulin (Ig) alleles play a pivotal role in the antibody response to pathogens, research to understand their role in the humoral immune response is still limited.MethodsWe retrieved the germline sequences for the IGHV from the IMGT database to illustrate the amino acid poly...

詳細記述

書誌詳細

主要な著者:	Weiqi Deng, Xuefeng Niu, Ping He, Qihong Yan, Huan Liang, Yongping Wang, Lishan Ning, Zihan Lin, Yudi Zhang, Xinwei Zhao, Liqiang Feng, Linbing Qu, Ling Chen
フォーマット:	Artigo
言語:	Inglês
出版事項:	Frontiers Media S.A. 2025-01-01
シリーズ:	Frontiers in Immunology
主題:	allele affinity antibody epitopes immunoglobulin heavy chain (Igh) neutralization
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1471396/full
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!