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Depressed glutamate transporter 1 expression in a mouse model of Dravet syndrome

Abstract Dravet syndrome (DS) is a monogenic, often refractory, epilepsy resultant from SCN1A haploinsufficiency in humans. A novel therapeutic target in DS that can be engaged in isolation or as adjunctive therapy is highly desirable. Here, we demonstrate reduced expression of the rodent glutamate...

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Principais autores: Mustafa Q. Hameed, Benjamin Hui, Rui Lin, Paul C. MacMullin, Andres Pascual‐Leone, Sheryl Anne D. Vermudez, Alexander Rotenberg
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2023-09-01
coleção:Annals of Clinical and Translational Neurology
Acesso em linha:https://doi.org/10.1002/acn3.51851
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