Depressed glutamate transporter 1 expression in a mouse model of Dravet syndrome
Abstract Dravet syndrome (DS) is a monogenic, often refractory, epilepsy resultant from SCN1A haploinsufficiency in humans. A novel therapeutic target in DS that can be engaged in isolation or as adjunctive therapy is highly desirable. Here, we demonstrate reduced expression of the rodent glutamate...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley
2023-09-01
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| Schriftenreihe: | Annals of Clinical and Translational Neurology |
| Online-Zugang: | https://doi.org/10.1002/acn3.51851 |
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