Current safety recommendations for handling mouse and human αsynuclein pre-formed fibrils

α-Synuclein (α-syn) can form amyloid fibrils. Lewy bodies and Lewy neurites containing aggregated α-syn are pathological markers of Parkinson's Disease and Dementia with Lewy Bodies. To better understand the role of pathological α-syn in disease, many labs use α-syn preformed fibrils (PFFs). Neurons...

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Principais autores:	Lauren Fielding, Marissa A. Menard, Justin Roth, Maria Iuliano, Benjamin Dehay, Patricia Aguilar-Calvo, Laura A. Volpicelli-Daley
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2025-03-01
叢編:	Neurobiology of Disease
主題:	Alpha-synuclein Biohazard Safety Amyloid Fibrils
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S0969996125000361
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