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Current safety recommendations for handling mouse and human αsynuclein pre-formed fibrils

α-Synuclein (α-syn) can form amyloid fibrils. Lewy bodies and Lewy neurites containing aggregated α-syn are pathological markers of Parkinson's Disease and Dementia with Lewy Bodies. To better understand the role of pathological α-syn in disease, many labs use α-syn preformed fibrils (PFFs). Neurons...

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Váldodahkkit: Lauren Fielding, Marissa A. Menard, Justin Roth, Maria Iuliano, Benjamin Dehay, Patricia Aguilar-Calvo, Laura A. Volpicelli-Daley
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2025-03-01
Ráidu:Neurobiology of Disease
Fáttát:
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S0969996125000361
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