Decapping factor Dcp2 controls mRNA abundance and translation to adjust metabolism and filamentation to nutrient availability

Degradation of most yeast mRNAs involves decapping by Dcp1/Dcp2. DEAD-box protein Dhh1 has been implicated as an activator of decapping, in coupling codon non-optimality to enhanced degradation, and as a translational repressor, but its functions in cells are incompletely understood. RNA-Seq analyse...

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Главные авторы:	Anil Kumar Vijjamarri, Xiao Niu, Matthew D Vandermeulen, Chisom Onu, Fan Zhang, Hongfang Qiu, Neha Gupta, Swati Gaikwad, Miriam L Greenberg, Paul J Cullen, Zhenguo Lin, Alan G Hinnebusch
Формат:	Artigo
Язык:	Inglês
Опубликовано:	eLife Sciences Publications Ltd 2023-06-01
Серии:	eLife
Предметы:	decapping degradation translation Dcp2 Dhh1 NMD
Online-ссылка:	https://elifesciences.org/articles/85545
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