The Role of the Ubiquitin-Proteasome System and p62 in the Development of Neurodegenerative Disease
The ubiquitin-proteasome system (UPS) is the pathway for degradation of nuclear and cytosolic proteins that are aged, damaged, or misfolded. Malfunctions in the UPS have been implicated in a wide variety of neurodegenerative diseases. Some proteins, when not properly degraded through the UPS, tend t...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Appalachian State University Dept of Psychology
2006-01-01
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| coleção: | Impulse: The Premier Undergraduate Neuroscience Journal |
| Assuntos: | |
| Acesso em linha: | http://impulse.appstate.edu/sites/impulse.appstate.edu/files/2006_05_Paine.pdf |
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