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The Role of the Ubiquitin-Proteasome System and p62 in the Development of Neurodegenerative Disease

The ubiquitin-proteasome system (UPS) is the pathway for degradation of nuclear and cytosolic proteins that are aged, damaged, or misfolded. Malfunctions in the UPS have been implicated in a wide variety of neurodegenerative diseases. Some proteins, when not properly degraded through the UPS, tend t...

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Principais autores: Michael G. Paine, Marie W. Wooten
Formato: Artigo
Idioma:Inglês
Publicado em: Appalachian State University Dept of Psychology 2006-01-01
coleção:Impulse: The Premier Undergraduate Neuroscience Journal
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Acesso em linha:http://impulse.appstate.edu/sites/impulse.appstate.edu/files/2006_05_Paine.pdf
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