Genetically engineered macrophages delivering TRAIL targeting the Wnt/β-catenin pathway to induce cytotoxicity against TNBC

Abstract Triple-negative breast cancer (TNBC) is a highly aggressive cancer subtype that lacks effective targeted therapies, posing significant challenges in its treatment. Engineered macrophages have emerged as promising tools for drug delivery and immunotherapy in cancer treatment. In this study,...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Mingyao Huang, Xin Yu, Zirong Jiang, Xiaofen Li, Shuo Yang, Shiping Luo, Chuangui Song
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2026-01-01
Sarja:	Cell Communication and Signaling
Aiheet:	TRAIL Engineered macrophages Pro-inflammatory TNBC Wnt/β-catenin
Linkit:	https://doi.org/10.1186/s12964-025-02394-7
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