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NOX2 activation contributes to cobalt nanoparticles-induced inflammatory responses and Tau phosphorylation in mice and microglia

Despite the wide application of cobalt nanoparticles (CoNPs), its neurotoxicity and the underlying mechanisms are not fully understood. In this study, CoNPs-induced toxic effect was examined in both C57BL/6J mice and microglial BV2 cells. CoNPs-induced brain weight loss and the reduction of Nissl bo...

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Bibliografiske detaljer
Principais autores: Jing Li, Junxiang Wang, Yuan-Liang Wang, Zhousong Luo, Chunyan Zheng, Guangxia Yu, Siying Wu, Fuli Zheng, Huangyuan Li
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-12-01
Serier:Ecotoxicology and Environmental Safety
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Online adgang:http://www.sciencedirect.com/science/article/pii/S014765132100837X
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