CD39 is an antibody-secreting B-cell marker that modulates germinal center and antibody responses during infection

CD39 is an ectoenzyme in immune cells that regulates purinergic signaling by converting extracellular ATP into adenosine (ADO). Although first described on EBV-transformed B cells, CD39’s role in humoral immunity remains unclear. Using murine infection models and human samples, we confirm and extend...

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Bibliografiska uppgifter

Huvudupphov:	Laura Almada, Yamila N. Gazzoni, Cristian G. Beccaria, Facundo Fiocca Vernengo, Santiago Boccardo, Melisa Gorosito Serrán, Apurwa Trivedi, Carola G. Vinuesa, Simon C. Robson, Eva V. Acosta Rodríguez, Mauro Gaya, Carolina L. Montes, Adriana Gruppi
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Frontiers Media S.A. 2025-10-01
Serie:	Frontiers in Immunology
Ämnen:	ADO Trypanosoma cruzi influenza virus antibody secreting cell (ASC) germinal center (GC) plasmablast
Länkar:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1547929/full
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