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Menin-MLL inhibitors as a new therapeutic target for middle ear cholesteatoma

Abstract Middle ear cholesteatoma (cholesteatoma), also known as a cholesteatomatous chronic otitis media, is concerning because it expands into the middle ear with bone destruction and causes irreversible hearing loss. Surgical resection is currently the only curative treatment, but the high recurr...

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Auteurs principaux: Tomomi Yamamoto-Fukuda, Naotaro Akiyama, Hiromi Kojima
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2026-01-01
Collection:Scientific Reports
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Accès en ligne:https://doi.org/10.1038/s41598-025-34922-3
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