Evaluation of the Pharmacokinetics of the Pancreastatin Inhibitor PSTi8 Peptide in Rats: Integration of In Vitro and In Vivo Findings

PSTi8 is a pancreastatin inhibitory peptide that is effective in the treatment of diabetic models. This study investigates the pharmacokinetic (PK) properties of PSTi8 in Sprague Dawley rats, for the first time. In vitro and in vivo PK studies were performed to evaluate the solubility, stability in...

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Principais autores:	Guru R. Valicherla, Roshan A. Katekar, Shailesh Dadge, Mohammed Riyazuddin, Anees A. Syed, Sandeep K. Singh, Athar Husain, Muhammad Wahajuddin, Jiaur R. Gayen
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2022-01-01
סדרה:	Molecules
נושאים:	antidiabetic drugs PSTi8 in vitro ADME in vivo pharmacokinetics bioavailability
גישה מקוונת:	https://www.mdpi.com/1420-3049/27/2/339
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