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Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors

Coumarin and chalcone, two important kinds of natural product skeletons, both exhibit α-glucosidase inhibitory activity. In this work, coumarin-chalcone derivatives 3 (a∼v) were synthesized, and their α-glucosidase inhibitory activity was screened. The results showed that all synthetic derivatives (...

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Detalhes bibliográficos
Principais autores: Chun-Mei Hu, Yong-Xin Luo, Wen-Jing Wang, Jian-Ping Li, Meng-Yue Li, Yu-Fei Zhang, Di Xiao, Li Lu, Zhuang Xiong, Na Feng, Chen Li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-06-01
coleção:Frontiers in Chemistry
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fchem.2022.926543/full
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