Design, Synthesis, In Silico Testing, and In Vitro Evaluation of Thiazolidinone-Based Benzothiazole Derivatives as Inhibitors of α-Amylase and α-Glucosidase

In this study, a stepwise reaction afforded thiazolidinone-based benzothiazole derivatives <b>1</b>–<b>15</b>, and the synthesized derivatives were then screened for biological significance and found to be the leading candidates against α-amylase and α-glucosidase enzymes. Almost all derivatives sho...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Shoaib Khan, Shahid Iqbal, Marwa Khan, Wajid Rehman, Mazloom Shah, Rafaqat Hussain, Liaqat Rasheed, Yousaf Khan, Ayed A. Dera, Rami Adel Pashameah, Eman Alzahrani, Abd-ElAziem Farouk
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	MDPI AG 2022-09-01
سلاسل:	Pharmaceuticals
الموضوعات:	synthesis α-amylase and α-glucosidase enzymes thiazolidinone benzothiazole SAR molecular docking
الوصول للمادة أونلاين:	https://www.mdpi.com/1424-8247/15/10/1164
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!