lncRNA Ubr5 promotes BMSCs apoptosis and inhibits their proliferation and osteogenic differentiation in weightless bone loss

BackgroundWeightless bone loss is a common pathological phenomenon in weightless environments, yet its specific molecular mechanism remain incompletely elucidated. The aim of this study was to systematically investigate the differential expression profiles of mRNAs and long noncoding RNAs (lncRNAs)...

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Principais autores:	Dong Wang, Yuan Gao, Yingjun Tan, Na Li, Xi Li, Jiaxiang Li, Yikai Pan, Xingcheng Zhao, Ming Yan, Yongchun Wang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2025-04-01
סדרה:	Frontiers in Cell and Developmental Biology
נושאים:	weightless bone loss lncRNA-mRNA coexpression network simulated weightlessness bone marrow mesenchymal stem cells lncRNA Ubr5
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1543929/full
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